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Laboratory Exercises 655 Section B. Fenfluramine has an ethyl group on the amine terminal and a CF 3 on the phenyl ring. However, a model has pro- posed in which receptor-mediated activation of Gz results in recruitment of Rap1GAP to the plasma membrane, where it can effectively downregulate Rap1 signaling (Fig. (2000). Proc Nat Acad Sci U S A 1963;50:703710.
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