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 proposed the entropy correlation coeYcient (ECC) technique to get a better registration result: ECC(X,Y) 14 2 I(X,Y) : H (X ) þ H (Y ) (8:27) Although the MI criterion has been widely used in registration of multimodal medical images of MRICT, MRIPET, CTPET, and CTSPECT, as pointed out by Maes and Suetens , registra- tion directly based on maximizing the MI criterion may not be able to get robust alignment of thorax CT and PET images.
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